Lab Test

Name

Book A Lab Visit

Comprehensive Hormones & NTMs

Dried Urine Test for Comprehensive Hormones (DUTCH Test)
Appointment
The lab tests are performed in an CLIA- and CAP-certified facility in USA
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Get 20% OFF on your first order. Subscribe to our newsletter and get your coupon!
Subscribe
Icon Rounded Arrow White - BRIX Templates

Why Urine Hormones?

This advanced hormone testing was developed to improve available hormone testing options. It offers the most extensive profile of sex and adrenal hormones along with their metabolites. Additionally, the daily (diurnal) pattern of free cortisol is included, along with melatonin (6OHMS), 8-OHdG and six organic acids. This unique combination of clinical information is not available by any other method.

Appointment
Instructions

Sample Type

Saliva

Methods Used

GC-MS/MS, LC-MS/MS

Requirement

4 Urine Samples Collection

Key Biomarkers

DUTCH Complete

Progesterone, Androgen, Estrogen Metabolites, Cortisol, Cortisone, Cortisol Metabolites, Creatinine, DHEA-S, OATs, Melatonin (6-OHMS), 8-OHdG

DUTCH Sex Hormone Metabolites

Progesterone, Androgen, Estrogen, and their Metabolites, DHEA

DUTCH Adrenal

Cortisol, Cortisol metabolites, Cortisone, Cortisone metabolites, THF, THE, DHEA

DUTCH OATs (Organic Acids)

HVA, VMA, MMA, Kynurenic Acid, Pyroglutamic Acid, 3-Hydroxyisovaleric Acid, Xanthurenic Acid, Quinolinic Acid, Melatonin, Indican, and 8-OHdG
Sample Reports
Clinical Importance

The DUTCH Test analyzes a patient's hormone levels in depth, providing you with all the information you need for a baseline hormone evaluation or monitoring hormone replacement therapy (HRT).

This useful tool can be used by healthcare providers to maximize hormone health and address hormone-related symptoms such as fatigue, weight gain, hair loss, and mood changes.

In addition to OATs, this test examines sex hormones and their metabolites, the overall diurnal pattern of free cortisol, and the total and distribution of cortisol metabolites.

Test Options

Most Comprehensive Test

DUTCH Complete
Dried Urine
14-21 Days
Progesterone, Androgen, Estrogen Metabolites, Cortisol, Cortisone, Cortisol Metabolites, Creatinine, DHEA-S, OATs, Melatonin (6-OHMS), 8-OHdG
Comprehensive assessment of hormones, metabolites and organic acids.

Female Focused

DUTCH Sex Hormone Metabolites
Dried Urine
14-21 Days
Progesterone, Androgen, Estrogen, and their Metabolites, DHEA
Baseline hormone metabolites measurement, providing insights into HRT monitoring.

Adrenal In-Depth

DUTCH Adrenal
Dried Urine
14-21 Days
Cortisol, Cortisol metabolites, Cortisone, Cortisone metabolites, THF, THE, DHEA
Free cortisol and cortisone patterns with the addition of metabolites for total cortisol production.

Nutritional & NTMs

DUTCH OATs
Dried Urine
14-21 Days
HVA, VMA, MMA, Kynurenic Acid, Pyroglutamic Acid, 3-Hydroxyisovaleric Acid, Xanthurenic Acid, Quinolinic Acid, Melatonin, Indican, and 8-OHdG
Include neurotransmitter metabolites, 9 nutritional organic acids, 8-OHdg, and melatonin.

Collection Instructions

You Must Read all of these first before collecting a sample!
Details
If you are taking hormones or supplements, please consult with your provider.
If you are a cycling woman, you must collect the samples on specific days of your cycles.
All samples must be fully dried before shipping them.
Please complete the test requisition form provided.
Preparation
Avoid Tyrosine, L-Dopa, D,L-Phenylalanine, Mucuna, Quercetin
Do not skip your hormones or birth control medications, if you taking Patch, Pellet or Injectable Hormones
If you are taking any steroids, consult with your healthcare provider

For cycling women, calculate collection dates according to the following formula

Length of cycles
Collection dates
X days
Day (9-X) - Day (6-X)
Example
28 days
Day 19 - 22
Collection Instructions
Complete all information on each collection device.
Saturate the filter paper by urinating directly on it or use a clean cup and dip the filter paper.
Leave the collection paper open to dry for at least
24 hours
Once dry, close each collection paper. Place all papers in the resealable plastic bag and return in the provided envelope.

Collection times below:

Basic Information

About DUTCH Test

There are several ways to test for hormones (saliva, serum and urine), but the state-of-the-art method is through saliva. This is because only the active portions of hormones are measured, and it is these portions that determine how individuals feel. So, if your patient is seeking bio-identical hormone replacement (BHRT), you will need to know active hormone levels. In addition, if using a topical (transdermal) hormone preparation for treatment, saliva testing is the most accurate tool to measure and monitor hormone status.

This useful tool can be used by healthcare providers to optimize hormone health and address hormone-related symptoms like fatigue, weight gain, hair loss, and mood changes.

Why Use DUTCH Test?

Most Advanced Urine Hormone Testing

This test analyzes sex hormones and their metabolites, the overall diurnal pattern of free cortisol, and the total and distribution of cortisol metabolites, in addition to OATs, which provide information on nutritional inadequacies, oxidative stress, gut dysbiosis, melatonin, neuroinflammation, and more.

The Easiest Patient Collection

Patients collect just 4 or 5 dried urine samples over a 24-hour period. Dried specimen shipments are convenient. Dried samples are stable for several weeks.

Analytical and Clinical Validation

This testing methods go through a rigorous validation process to verify accuracy, recovery, and linearity. We pride ourselves in relentlessly pursuing the most accurate and precise techniques available for testing.

Dried Urine vs Saliva
No measured hormone metabolites
Convenient, non-invasive
No cortisol clearance
Only free hormones
Dried vs 24-hr Urine
Difficult to collect
More expensive
Cannot assess diurnal pattern
High error rate
Dried Urine vs Blood
Standardized
Invasive, need blood draw
Cannot assess diurnal pattern
No measured hormone metabolites
Risk of overestimation

Lab Comparison

Compare the Advantage of Blood vs Saliva vs Urine Hormone Testing
Blood
Test for total hormone levels
Saliva
Test for free forms of hormones
Urine
Test for all forms of hormones
Free Cortisol
Limited
Diurnal Cortisol Pattern
DHEA
Free Forms of Sex Hormones
Sex Hormone Metabolites

Compare the Blood vs Saliva vs Urine Hormone Testing

Blood

Test for total hormone levels

Saliva

Test for free forms of hormones

Urine

Test for all forms of hormones
Free Cortisol
Limited
Diurnal Cortisol Pattern
DHEA
Free Form of Sex Hormones
Sex Hormone Metabolites

Basic plan

$96/year
Basic features for up to 10 users with everything you need.
Get started

Business plan

$192/year
Advanced features and reporting, better workflows and automation.
Get started

Enterprise plan

$384/year
Personalised service and enterprise security for large teams.
Get started
User access
Basic features
Saved reports
10
20
Unlimited
Individual data
20GB
40GB
Unlimited
Support
Automated workflows
200+ integrations
Reporting and analytics
Analytics
Basic
Advanced
Advanced
Export reports
Scheduled reports
API access
Advanced reports
Saved reports
Customer properties
Custom fields
User access
SSO/SAML authentication
Advanced permissions
Audit log
Data history

Symptoms of Hormone Imbalance

Estrogen

Test for total hormone levels

Progesterone

Test for free forms of hormones

Glucocorticoids

Test for all forms of hormones

DHEA

Test for all forms of hormones

DHEA

Test for all forms of hormones
Women Common Symptoms
Hot flashes
Limited
Night sweats
Headaches
Hair loss
Poor sleep
Anxiety
Depression
Stress
Low libido
Memory loss
Sugar cravings
Weight gain
Facial hair/acne
Men Common Symptoms
SSO/SAML authentication
Advanced permissions
Audit log
Data history

Basic plan

$96/year
Basic features for up to 10 users with everything you need.
Get started

Business plan

$192/year
Advanced features and reporting, better workflows and automation.
Get started

Enterprise plan

$384/year
Personalised service and enterprise security for large teams.
Get started
User access
Basic features
Saved reports
10
20
Unlimited
Individual data
20GB
40GB
Unlimited
Support
Automated workflows
200+ integrations
Reporting and analytics
Analytics
Basic
Advanced
Advanced
Export reports
Scheduled reports
API access
Advanced reports
Saved reports
Customer properties
Custom fields
User access
SSO/SAML authentication
Advanced permissions
Audit log
Data history